Wednesday October 10
08:30 Registration
Keynote lectures
Chair intro: Meryl S. Lillenes
9:00 – Melanie Blokesch, Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland:
“Genome Maintenance – or NOT – in Vibrio cholera”
9:45 – Dale B. Wigley, Imperial College London, UK:
“RecBCD/AddAB : Machines for processing DNA breaks”
10:30 – Coffee
Session 1 – DNA repair
Chair intro: Christopher L. Bayliss
11:00 – David Leach, University of Edinburgh, Scotland:
“Heritable Cell Division-Dependent Breakage of the E. coli Chromosome Terminus in the Absence of RecBCD Enzyme”
11:20 – Kirsten Skarstad, Oslo University Hospital, Norway:
“Replication fork stability and salvage in Escherichia coli and Vibrio cholerae”
11:40 – Lene Juel Rasmussen,University of Copenhagen, Denmark:
“Guarding the genomes”
Lunch 12.00 – 13.00
Session 2 – Horizontal gene transfer and antimicrobial resistance (AMR)
Chair intro: Tone Tønjum
13:00 – Dan I. Andersson, University of Uppsala, Sweden:
“Mechanisms and consequences of unstable antibiotic resistance”
13:20 – Ivan Matic, Inserm, Necker Medical School, France:
“DNA repair kills trimethoprim-treated cells”
13:40 – Maria Sandkvist, University of Michigan, USA:
“Acinetobacter baumannii and the type II secretion system”
14.00 – Coffee
Session 3 – Genome instability, microbe-host interactions and AMR
Chair intro: Jessica Lönn-Stensrud
14:20 – Josep Casadesus, Universidad de Sevilla, Spain:
“Non-mutational preadaptation to lethal selection”
14:40 – Duccio Medini, GSK, Italy:
“Meningococcal genomic population structure and antigen variability: Genetic predictors of 4CMenB vaccine strain coverage”
15:00 – Tone Tønjum, University of Oslo, Norway:
“The human microbiome as a dynamic harbor for AMR”
15:20 – Coffee and snacks
16:00 – Christopher Bayliss, University of Leicester, UK:
“Hypermutable sequences as mediators of phage resistance”
16:20 – David Grainger, University of Birmingham, UK:
“Understanding toxic DNA sequences in bacterial genomes”
16:40 – Jay Hinton, University of Liverpool, UK:
“Comparative transcriptomics identifies a single SNP mutation that controls virulence of African Salmonella”
Poster viewing
17.00 – 18.30 – Poster viewing – Selection of poster prizes
19:00 – Dinner at Holmen Fjordhotell
Dinner speech:
CEO Bjørn Erikstein, Oslo University Hospital, Norway