Wednesday October 10

08:30 Registration

Keynote lectures

Chair intro: Meryl S. Lillenes

9:00 – Melanie Blokesch, Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland:
“Genome Maintenance – or NOT – in Vibrio cholera”

9:45 – Dale B. Wigley, Imperial College London, UK:
“RecBCD/AddAB : Machines for processing DNA breaks”

10:30 – Coffee

Session 1 – DNA repair

Chair intro: Christopher L. Bayliss

11:00 – David Leach, University of Edinburgh, Scotland:
“Heritable Cell Division-Dependent Breakage of the E. coli Chromosome Terminus in the Absence of RecBCD Enzyme”

11:20 – Kirsten Skarstad, Oslo University Hospital, Norway:
“Replication fork stability and salvage in Escherichia coli and Vibrio cholerae”

11:40 – Lene Juel Rasmussen,University of Copenhagen, Denmark:
Guarding the genomes”

Lunch   12.00 – 13.00

Session 2 – Horizontal gene transfer and antimicrobial resistance (AMR)

Chair intro: Tone Tønjum

13:00 – Dan I. Andersson, University of Uppsala, Sweden:
“Mechanisms and consequences of unstable antibiotic resistance”

13:20 – Ivan Matic, Inserm, Necker Medical School, France:
“DNA repair kills trimethoprim-treated cells”

13:40 – Maria Sandkvist, University of Michigan, USA:
“Acinetobacter baumannii and the type II secretion system”

14.00 – Coffee

Session 3 – Genome instability, microbe-host interactions and AMR

Chair intro: Jessica Lönn-Stensrud

14:20 – Josep Casadesus, Universidad de Sevilla, Spain:
“Non-mutational preadaptation to lethal selection”

14:40 – Duccio Medini, GSK, Italy:
“Meningococcal genomic population structure and antigen variability: Genetic predictors of 4CMenB vaccine strain coverage”

15:00 – Tone Tønjum, University of Oslo, Norway:
“The human microbiome as a dynamic harbor for AMR”

15:20 – Coffee and snacks

16:00 – Christopher Bayliss, University of Leicester, UK:
“Hypermutable sequences as mediators of phage resistance”

16:20 – David Grainger, University of Birmingham, UK:
“Understanding toxic DNA sequences in bacterial genomes”

16:40 – Jay Hinton, University of Liverpool, UK:
“Comparative transcriptomics identifies a single SNP mutation that controls virulence of African Salmonella”

Poster viewing

17.00 – 18.30 – Poster viewing – Selection of poster prizes

19:00 – Dinner at Holmen Fjordhotell

Dinner speech:
CEO Bjørn Erikstein, Oslo University Hospital, Norway


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